- Matsuda S, Okada R, Tandhvanant S, Hiyoshi H, Gotoh K, Iida T, Kodama T.
Export of a Vibrio parahaemolyticus toxin by the Sec and type III secretion machineries in tandem.
Nat Microbiol. 4:781-788, 2019 - Le-Ha T-D, Le L, Le-Vo H-N, Anda M, Motooka D, Nakamura S, Tran L, Tran P, Iida T, Cao V.
Characterization of a carbapenem- and colistin-resistant Enterobacter cloacae carrying Tn6901 in blaNDM-1 genomic context.
Infection and Drug Resistance. 12:733-739, 2019 - Tanimoto Y, Tamai S, Matsuzaki T, Takeuchi N, Noju T, Yanagida S, Kage-Nakadai E, Yamaguchi Y, Kodama T, Nakamura S, Motooka D, Iida T, Nishikawa Y.
Diffusely adherent Escherichia coli strains isolated from healthy carriers suppress cytokine secretions of epithelial cells stimulated by inflammatory substances.
Infect Immun. 87:e00683-18, 2018 - Tandhavanant S, Matsuda S, Hiyoshi H, Iida T, Kodama T.
Vibrio parahaemolyticus senses intracellular K+ to translocate type III secretion system 2 effectors effectively.
mBio. 9:e01366-18, 2018 - Oki H, Kawahara K, Maruno T, Imai T, Muroga Y, Fukakusa S, Iwashita T, Kobayashi Y, Matsuda S, Kodama T, Iida T, Yoshida T, Ohkubo T, Nakamura S.
Interplay of a secreted protein with type IVb pilus for efficient enterotoxigenic Escherichia coli colonization.
Proc Natl Acad Sci U S A. 115:7422-7427, 2018 - Katsimichas T, Ohtani T, Motooka D, Tsukamoto Y, Kioka H, Nakamoto K, Konishi S, Chimura M, Sengoku K, Miyawaki H, Sakaguchi T, Okumura R, Theofilis K, Iida T, Takeda K, Nakamura S, Sakata Y.
Non-ischemic heart failure with reduced ejection fraction is associated with altered intestinal microbiota.
Circ J. 82:1640-1650, 2018 - Yoshizawa H, Motooka D, Matsumoto Y, Katada R, Nakamura S, Morii E, Iida T, Matsumoto H.
A case of severe soft tissue infection due to Streptococcus tigurinus diagnosed by necropsy in which genomic analysis was useful for clarifying its pathogenicity.
Pathol Int. 68:301-306, 2018 - Aoki K, Harada S, Yahara K, Ishii Y, Motooka D, Nakamura S, Akeda Y, Iida T, Tomono K, Iwata S, Moriya K, Tateda K.
Molecular characterization of IMP-1-producing Enterobacter cloacae complex isolates in Tokyo.
Antimicrob Agents Chemother. 62:e02091-17, 2018 - Okada R, Matsuda S, Iida, T.
Vibrio parahaemolyticus VtrA is a membrane-bound regulator and is activated via oligomerization.
PLoS One. 12:e0187846, 2017 - Yoshizawa H, Motooka D, Katada R, Matsumoto Y, Nakamura S, Morii E, Iida T, Matsumoto H.
Whole genome sequence of Streptococcus tigurinus strain osk_001, isolated from the post-mortem material.
Genome Announcements. 5:e00878-17, 2017 - Motooka D, Fujimoto K, Tanaka R, Yaguchi T, Gotoh K, Maeda Y, Furuta Y, Kurakawa T, Goto N, Yasunaga T, Narazaki M, Kumanogoh A, Horii T, Iida T, Takeda K, Nakamura S.
Fungal ITS1 deep-sequencing strategies to reconstruct the composition of a 26-species community and evaluation of the gut mycobiota of healthy Japanese individuals.
Front Microbiol. 8: 238, 2017 - Kawai S, Iijima H, Shinzaki S, Hiyama S, Yamaguchi T, Araki M, Iwatani S, Shiraishi E, Mukai A, Inoue T, Hayashi Y, Tsujii M, Motooka D, Nakamura S, Iida T, Takehara T.
Indigo Naturalis ameliorates murine dextran sodium sulfate-induced colitis via aryl hydrocarbon receptor activation.
J Gastroenterol. 52:904-919, 2017 - Theethakaew C, Nakamura S, Motooka D, Matsuda S, Kodama T, Chonsin K, Suthienkul O, Iida T.
Plasmid dynamics in Vibrio parahaemolyticus strains related to shrimp Acute Hepatopancreatic Necrosis Syndrome (AHPNS).
Infect Genet Evol. 51:211-218, 2017 - Takino T, Kato-Mori Y, Motooka D, Nakamura S, Iida T, Hagiwara K.
Postnatal changes in the relative abundance of intestinal Lactobacillus spp. in newborn calves.
J Vet Med Sci. 79:452-455, 2017 - Wake N, Asahi Y, Noiri Y, Hayashi M, Motooka D, Nakamura S, Gotoh K, Miura J, Machi H, Iida T, Ebisu S.
Temporal dynamics of bacterial microbiota in the human oral cavity determined using an in situ model of dental biofilms.
NPJ Biofilms and Microbiomes. 2:16018, 2016 - Hagiya H, Yoshida H, Shimizu M, Motooka D, Nakamura S, Iida T, Yamamoto N, Akeda Y, Tomono K.
Herpes zoster laryngitis in a patient treated with fingolimod.
J Infect Chemother. 22:830-832, 2016 - Kawahara K, Yonogi S, Munetomo R, Oki H, Yoshida T, Kumeda Y, Matsuda S, Kodama T, Ohkubo T, Iida T, Nakamura S.
Crystal structure of the ADP-ribosylating component of BEC, the binary enterotoxin of Clostridium perfringens.
Biochem Biophys Res Commun. 480:261-267, 2016 - Maeda Y, Kurakawa T, Umemoto E, Motooka D, Ito Y, Gotoh K, Hirota K, Matsushita M, Furuta Y, Narazaki M, Sakaguchi N, Kayama H, Nakamura S, Iida T, Saeki Y, Kumanogoh A, Sakaguchi S, Takeda K.
Dysbiosis contributes to arthritis development via activation of autoreactive T cells in the intestine.
Arthritis Rheumatol. 68:2646-2661, 2016 - Yonogi S, Kanki M, Ohnishi T, Shiono M, Iida T, Kumeda Y.
Development and application of a multiplex PCR assay for detection of the Clostridium perfringens enterotoxin-encoding genes cpe and becAB.
J Microbiol Methods. 127:172-175, 2016 - M. Ojima, D. Motooka, K. Shimizu, K. Gotoh, A. Shintani, K. Yoshiya, S. Nakamura, H. Ogura, T. Iida and T. Shimazu.
Metagenomic Analysis Reveals Dynamic Changes of Whole Gut Microbiota in the Acute Phase of Intensive Care Unit Patients.
Dig Dis Sci. 61:1628-1634, 2016 - Kawahara K, Oki H, Fukakusa S, Yoshida T, Imai T, Maruno T, Kobayashi Y, Motooka D, Iida T, Ohkubo T, Nakamura S.
Homo-trimeric structure of the type IVb minor pilin CofB suggests mechanism of CFA/III pilus assembly in human enterotoxigenic Escherichia coli.
J Mol Biol. 428:1209-1126, 2016 - Okumura R, Kurakawa T, Nakano T, Kayama H, Kinoshita M, Motooka D, Gotoh K, Kimura T, Kamiyama N, Kusu T, Ueda Y, Wu H, Iijima H, Barman S, Osawa H, Matsuno H, Nishimura J, Ohba Y, Nakamura S, Iida T, Yamamoto M, Umemoto E, Sano K, Takeda K.
Lypd8 promotes the segregation of flagellated microbiota and colonic epithelia.
Nature. 532:117-121, 2016 - K. Chonsin, S. Matsuda, C. Theethakaew, T. Kodama, J. Junjhon, Y. Suzuki, O. Suthienkul and T. Iida.
Genetic diversity of Vibrio parahaemolyticus strains isolated from farmed Pacific white shrimp and ambient pond water affected by acute hepatopancreatic necrosis disease outbreak in Thailand.
FEMS Microbiol Lett. 363:, 2016 - Kawahara K, Oki H, Fukakusa S, Maruno T, Kobayashi Y, Motooka D, Taniguchi T, Honda T, Iida T, Nakamura S, Ohkubo T.
Cloning, expression, purification, crystallization and X-ray crystallographic analysis of CofB, the minor pilin subunit of CFA/III from human enterotoxigenic Escherichia coli.
Acta Crystallogr F Struct Biol Commun. 71:663-667, 2015 - Meirelles PM, Amado-Filho GM, Pereira-Filho GH, Pinheiro HT, de Moura RL, Joyeux JC, Mazzei EF, Bastos AC, Edwards RA, Dinsdale E, Paranhos R, Santos EO, Iida T, Gotoh K, Nakamura S, Sawabe T, Rezende CE, Gadelha LM Jr, Francini-Filho RB, Thompson C, Thompson FL.
Baseline Assessment of Mesophotic Reefs of the Vitória-Trindade Seamount Chain Based on Water Quality, Microbial Diversity, Benthic Cover and Fish Biomass Data.
PLoS One. 10:e130084, 2015 - M. Nishimura, T. Fujii, H. Hiyoshi, F. Makino, H. Inoue, D. Motooka, T. Kodama, T. Ohkubo, Y. Kobayashi, S. Nakamura, K. Namba and T. Iida.
A repeat unit of Vibrio diarrheal T3S effector subverts cytoskeletal actin homeostasis via binding to interstrand region of actin filaments.
Sci Rep. 5:10870, 2015 - H. Hiyoshi, R. Okada, S. Matsuda, K. Gotoh, Y. Akeda, T. Iida and T. Kodama.
Interaction between the Type III Effector VopO and GEF-H1 Activates the RhoA-ROCK Pathway.
PLoS Pathog. 11:e1004694, 2015 - M. Okamoto, T. Miyazawa, S. Morikawa, F. Ono, S. Nakamura, E. Sato, T. Yoshida, R. Yoshikawa, K. Sakai, T. Mizutani, N. Nagata, J. Takano, S. Okabayashi, M. Hamano, K. Fujimoto, T. Nakaya, T. Iida, T. Horii, T. Miyabe-Nishiwaki, A. Watanabe, A. Kaneko, A. Saito, A. Matsui, T. Hayakawa, J. Suzuki, H. Akari, T. Matsuzawa and H. Hirai.
Emergence of infectious malignant thrombocytopenia in Japanese macaques (Macaca fuscata) by SRV-4 after transmission to a novel host.
Sci Rep. 5:8850, 2015 - N. Alves Junior, P. M. Meirelles, E. de Oliveira Santos, B. Dutilh, G. G. Silva, R. Paranhos, A. S. Cabral, C. Rezende, T. Iida, R. L. de Moura, R. H. Kruger, R. C. Pereira, R. Valle, T. Sawabe, C. Thompson and F. Thompson.
Microbial community diversity and physical-chemical features of the Southwestern Atlantic Ocean.
Arch Microbiol. 197:165-79, 2015 - T. Kodama, H. Hiyoshi, R. Okada, S. Matsuda, K. Gotoh and T. Iida.
Regulation of Vibrio parahaemolyticus T3SS2 gene expression and function of T3SS2 effectors that modulate actin cytoskeleton.
Cell Microbiol. 17:183-90, 2015 - K. Hosomi, Y. Sakaguchi, T. Kohda, K. Gotoh, D. Motooka, S. Nakamura, K. Umeda, T. Iida, S. Kozaki and M. Mukamoto.
Complete nucleotide sequence of a plasmid containing the botulinum neurotoxin gene in Clostridium botulinum type B strain 111 isolated from an infant patient in Japan.
Mol Genet Genomics. 289:1267-74, 2014 - M. Miyamoto, D. Motooka, K. Gotoh, T. Imai, K. Yoshitake, N. Goto, T. Iida, T. Yasunaga, T. Horii, K. Arakawa, M. Kasahara and S. Nakamura.
Performance comparison of second- and third-generation sequencers using a bacterial genome with two chromosomes.
BMC Genomics. 15:699, 2014 - S. Yonogi, S. Matsuda, T. Kawai, T. Yoda, T. Harada, Y. Kumeda, K. Gotoh, H. Hiyoshi, S. Nakamura, T. Kodama and T. Iida.
BEC, a novel enterotoxin of Clostridium perfringens found in human clinical isolates from acute gastroenteritis outbreaks.
Infect Immun. 82:2930-9, 2014 - R. Okada, X. Zhou, H. Hiyoshi, S. Matsuda, X. Chen, Y. Akeda, T. Kashimoto, B. M. Davis, T. Iida, M. K. Waldor and T. Kodama.
The Vibrio parahaemolyticus effector VopC mediates Cdc42-dependent invasion of cultured cells but is not required for pathogenicity in an animal model of infection.
Cell Microbiol. 16:938-47, 2014 - S. Hiyama, H. Iijima, S. Shinzaki, T. Inoue, E. Shiraishi, S. Kawai, M. Araki, M. Kato, Y. Hayashi, T. Nishida, H. Fujii, A. Mukai, N. Shibata, S. Sato, H. Kiyono, K. Gotoh, D. Motooka, S. Nakamura, T. Iida, M. Tsujii and T. Takehara.
Peyer's patches play a protective role in nonsteroidal anti-inflammatory drug-induced enteropathy in mice.
Inflamm Bowel Dis. 20:790-9, 2014 - K. Arimatsu, H. Yamada, H. Miyazawa, T. Minagawa, M. Nakajima, M. I. Ryder, K. Gotoh, D. Motooka, S. Nakamura, T. Iida and K. Yamazaki.
Oral pathobiont induces systemic inflammation and metabolic changes associated with alteration of gut microbiota.
Sci Rep. 6:4828, 2014 - K. Masahata, E. Umemoto, H. Kayama, M. Kotani, S. Nakamura, T. Kurakawa, J. Kikuta, K. Gotoh, D. Motooka, S. Sato, T. Higuchi, Y. Baba, T. Kurosaki, M. Kinoshita, Y. Shimada, T. Kimura, R. Okumura, A. Takeda, M. Tajima, O. Yoshie, M. Fukuzawa, H. Kiyono, S. Fagarasan, T. Iida, M. Ishii and K. Takeda.
Generation of colonic IgA-secreting cells in the caecal patch.
Nat Commun. 10:3704, 2014 - M. Seki, H. Yoshida, K. Gotoh, N. Hamada, D. Motooka, S. Nakamura, N. Yamamoto, S. Hamaguchi, Y. Akeda, H. Watanabe, T. Iida and K. Tomono.
Severe respiratory failure due to co-infection with human metapneumovirus and Streptococcus pneumoniae.
Respiratory Medicine Case Reports. 12:13-15, 2014 - Imai A, Gotoh K, Asano Y, Yamada N, Motooka D, Fukushima M, Kanzaki M, Ohtani T, Sakata Y, Nishi H, Toda K, Sawa Y, Komuro I, Horii T, Iida T, Nakamura S, Takashima S.
Comprehensive metagenomic approach for detecting causative microorganisms in culture-negative infective endocarditis.
Int J Cardiol. 172:e288-e289, 2014 - Masafumi Seki, Hideaki Ohno, Kazuyoshi Gotoh, Daisuke Motooka, Shota Nakamura, Tetsuya Iida, Yoshitsugu Miyazaki, Kazunori Tomono.
Allergic bronchopulmonary mycosis due to co-infection with Aspergillus fumigatus and Schizophyllum commune.
ID Cases. 1:5-8, 2014 - Cavalcanti GS, Gregoracci GB, dos Santos EO, Silveira CB, Meirelles PM, Longo L, Gotoh K, Nakamura S, Iida T, Sawabe T, Rezende CE, Francini-Filho RB, Moura RL, Amado-Filho GM, Thompson FL.
Physiologic and metagenomic attributes of the rhodoliths forming the largest CaCO3 bed in the South Atlantic Ocean.
ISME J. 8:52-62, 2014 - Cavalcanti, Giselle S.; Gregoracci, Gustavo B.; Longo, Leila de L.; Bastos, Alex C.; Ferreira, Camilo M.; Francini-Filho, Ronaldo B.; Paranhos, Rodolfo; Ghisolfi, Renato D.; Krueger, Ricardo; Gueth, Arthur Z.; Sumida, Paulo Y. G.; Bruce, Thiago; Maia-Neto, Oswaldo; Santos, Eidy de O.; Iida, Tetsuya; Moura, Rodrigo L.; Amado-Filho, Gilberto M.; Thompson, Fabiano L.
Sinkhole-like structures as bioproductivity hotspots in the Abrolhos Bank.
CONTINENTAL SHELF RESEARCH. 70:126-134, 2013 - Matsuo T, Nakamura K, Kodama T, Mikami T, Hiyoshi H, Tsuchiya T, Ogawa W, Kuroda T.
Characterization of all RND-type multidrug efflux transporters in Vibrio parahaemolyticus.
Microbiologyopen. 2:725-42, 2013 - Seki M, Gotoh K, Nakamura S, Akeda Y, Yoshii T, Miyaguchi S, Inohara H, Horii T, Oishi K, Iida T, Tomono K.
Fatal sepsis caused by an unusual Klebsiella species that was misidentified by an automated identification system.
J Med Microbiol. 62:801-3, 2013 - G. D. Garcia, G. B. Gregoracci, E. D. Santos, P. M. Meirelles, G. G. Z. Silva, R. Edwards, T. Sawabe, K. Gotoh, S. Nakamura, T. Iida, R. L. de Moura and F. L. Thompson.
Metagenomic Analysis of Healthy and White Plague-Affected Mussismilia braziliensis Corals.
Microb Ecol. 65:1076-1086, 2013 - Morita M, Yamamoto S, Hiyoshi H, Kodama T, Okura M, Arakawa E, Alam M, Ohnishi M, Izumiya H, Watanabe H.
Horizontal gene transfer of a genetic island encoding a type III secretion system distributed in Vibrio cholerae.
Microbiol Immunol. 57:334-9, 2013 - Monira S, Nakamura S, Gotoh K, Izutsu K, Watanabe H, Alam NH, Nakaya T, Horii T, Ali SI, Iida T.
Metagenomic profile of gut microbiota in children during cholera and recovery.
Gut Pathog. 5:1, 2013 - N. Higa, C. Toma, Y. Koizumi, N. Nakasone, T. Nohara, J. Masumoto, T. Kodama, T. Iida and T. Suzuki.
Vibrio parahaemolyticus Effector Proteins Suppress Inflammasome Activation by Interfering with Host Autophagy Signaling.
PLoS Pathog. 9:e1003142, 2013 - Yasugi, M., Nakamura, S., Daidoji, T., Kawashita, N., Ramadhany, R., Yang, C.-S., Yasunaga, T., Iida, T., Horii, T., Ikuta, K., Takahashi, K. and Nakaya, T.
Frequency of D222G and Q223R hemagglutinin mutants of pandemic (H1N1) 2009 influenza virus in Japan between 2009 and 2010.
PLoS One. 7:e30946, 2012 - Ritchie, J. M., Rui, H., Zhou, X., Iida, T., Kodoma, T., Bronson, R. T., Ito, S., Davis, B. M. and Waldor, M. K.
Inflammation and disintegration of intestinal villi in an experimental model for Vibrio parahaemolyticus-induced diarrhea.
PLoS Pathog. 8:e1002593, 2012 - Zhou, X, Ritchie, J. M., Hiyoshi, H., Iida, T., Davis, B. M., Waldor, M. K. and Kodama, T.
The hydrophilic translocator for Vibrio parahaemolyticus T3SS2 is also translocated.
Infect Immun. 80:2940-2947, 2012 - Matsuda, S., Okada, N., Kodama, T., Honda, T. and Iida, T.
A cytotoxic type III secretion effector of Vibrio parahaemolyticus targets vacuolar H+-ATPase c subunit and rupture host cell lysosomes.
PLoS Pathog. 8:e1002803, 2012 - Fukakusa, S., Kawahara, K., Nakamura, S., Iwashita, T., Baba, S., Nishimura, M., Kobayashi, Y., Honda, T., Iida, T., Taniguchi, T. and Ohkubo, T.
Crystal structure of the CFA/III major pilin subunit CofA from human enterotoxigenic Escherichia coli determined at 0.90 Å by sulphur-SAD phasing.
Acta Crystallogr D. 68:1418-1429, 2012 - Akeda, Y., Kimura, T., Yamasaki, A., Kodama, T., Iida, T., Honda, T. and Oishi, K.
Functional cloning of Vibrio parahaemolyticus type III secretion system 1 in E. coli K-12 strain as a molecular syringe.
Biochem Biophys Res Com. 427:242-247, 2012 - Puiprom, O., Chantaroj, S., Matsuda, S., Sawanpanyalert, P., Honda, T., Iida, T. and Taniguchi, T.
Immun response in diarrheal patients and asymptomatic carrier with CS6-producing enterotoxigenic Escherichia coli infection.
Southeast Asian J Trop Med Public Health. 43:1452-1460, 2012 - Thompson, F.L., Neto, A.A., Santos, E., Izutsu, K. and Iida, T.
Effect of N-acetyl-D-glucosamine on gene expression in Vibrio parahaemolyticus.
Microb Environ. 26:61-66, 2011 - Thompson, C. C., Abato, M. M., Dias, G. M., Dutilh, B. E. Edwards, R. A., Iida, T., Thompson, F. L. and Vicente, A. C. P.
Genome sequence of the human pathogen Vibrio cholerae Amazonia.
J Bacteriol. 193:5877-5878, 2011 - Akeda, Y., Kodama, T, Saito, K., Iida, T., Oishi, K. and Honda, T.
Identification of the Vibrio parahaemolyticus type III secretion system 2-associated chaperone VocC for the T3SS2-specific effector VopC.
FEMS Microbiol Lett. 324:156-164, 2011 - Abolghait, S. K., Iida, T., Kodama, T., Cantarelli, V. V., Akeda, Y. and Honda, T.
Recombinant AexU effector protein of Aeromonas veronii bv. sobria disrupts the actin cytoskeleton by downregulation of Rac1 and induces direct cytotoxicity to ß4-integrin expressing cell lines.
Microb Pathog. 51:454-465, 2011 - Sugiyama, H., Kashimoto, T., Ueno, S., Ehara, H., Kodama, T., Iida, T. and Susa, N.
Relationship between localization on cellular membranes and cytotoxicity of Vibrio vulnificus hemolysin.
PLoS One. 6:e26018, 2011 - Hiyoshi, H., Kodama, T., Saito, K., Gotoh K., Akeda, Y., Honda, T. and Iida, T.
VopV, an F-actin binding type III secretion effector, is required for Vibrio parahaemolyticus-induced enterotoxicity.
Cell Host Microbe. 10:401-409, 2011 - Monira, S., Nakamura, S., Gotoh, K.,Izutsu, K., Watanabe, H., Alam, N. H., Endtz, H. P., Cravioto, A., Ali, S. I., Nakaya, T., Horii, T., Iida, T. and Alam, M.
Gut microbiota of healthy and malnourished children in Bangladesh.
Front Microbiol. 2:228, 2011
